Our Work

Comprehensive COVID-19 Study Services

The COVID-19 pandemic has posed unprecedented challenges and opened new frontiers in medical research. Gnome Sciences, at the forefront of this scientific endeavor, provides a comprehensive suite of molecular biology and pathology lab services to support clinicians and researchers in their study of COVID-19. Our work spans the creation of laboratory-developed tests (LDT) for SARS-CoV-2 RNA, reporting results for numerous patients, and contributing leading-edge scientific reports about COVID-19 infections and complications. Our precision laboratory research services are carried out in our CLIA-certified molecular biology and pathology laboratories, overseen by board-certified pathologists and seasoned laboratory staff, ensuring top quality results with rapid turnaround times.

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COVID-19 Study Services

Gnome Sciences boasts an expansive range of services designed to detect and analyze the SARS-CoV-2 virus. These services leverage our rich biorepository that contains hundreds of formalin-fixed, paraffin-embedded blocks from autopsies of fatal COVID-19 cases, encompassing most major organs. Our repository also includes hundreds of slides from individuals with skin lesions associated with either SARS-CoV-2 or the vaccine, with comprehensive clinical information attached to each biopsy and autopsy.


Our team excels at detecting viral RNA and proteins in formalin-fixed, paraffin-embedded tissues in situ, and outlining the concurrent host response using advanced co-localization experiments and software. This expertise is evidenced in the numerous peer-reviewed papers we have published.


We have also honed protocols to extract and analyze viral proteins via ELISA, dot blot hybridization, and Western blot analyses. In addition, our experience in qRT-PCR analysis of RNA extracted from formalin-fixed, paraffin-embedded tissues, including variant detection, is second to none. Finally, our vast library of nasopharyngeal swabs, already analyzed for viral RNA, can be harnessed for additional solution phase work or in situ localization of the virus and host response.


Recognizing the variation of data on key biomarkers in COVID-19 cases across different laboratories, we strive for standardization. We have developed and published numerous papers on the detection of COVID-19 markers in human tissues. Our Reference Lab services offer standardized protocols to perform histopathology services on samples from diverse collections and studies, thus normalizing protein expression detection and ISH across specimens.

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IHC Image Portfolio: Our Work in Focus

Explore a selection of the thousands of IHC images we’ve meticulously developed, both internally and for our valued clients.

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1476 Manning Parkway
Powell, Ohio 43065

(614) 431-6414

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