Unparalleled Preclinical Biomarker Services for Drug Discovery & Development
Navigating the intricate journey of drug discovery and development demands robust scientific support and expertise. Gnome Sciences emerges as your reliable partner in this quest, offering an array of comprehensive solutions tailor-made to support and accelerate your drug development process. Our team of seasoned scientists, proficient pathologists, and industry veterans pledge to work in unison with you, ensuring every milestone in your drug development journey is marked with precision, efficiency, and success.
Discuss your preclinical biomarker service needs with our scientists.
Our Expertise
At Gnome Sciences, we understand the critical role that preclinical biomarker services play in pharmaceutical and biotech research. Our dedication to this aspect of drug discovery and development has positioned us as a leading provider of comprehensive solutions in the field. We channelize our expertise, technologies, and comprehensive service range to help identify and validate potential drug targets, thereby catalyzing your drug development process.
Our Services Include
We offer a vast array of services to meet the dynamic needs of drug discovery and development. These include Biomarker Identification and Validation, vital for ensuring the feasibility and potential success of a therapeutic candidate. We provide Tissue Analysis for Target Engagement and Expression and Drug-induced pathway activation analysis through Gene or Protein Expression/ Co-expression. We also study the Biological impact of therapeutics via on/off-target analysis of proteins, tissue and cell-based analysis, and multiplex/co-expression analysis. These services form the bedrock of our comprehensive preclinical biomarker services portfolio.
Additional Method Development, Validation, & Execution Services incorporate:
- Protocol design and development
- Assay Development
- Method validation
- Guidance on method selection
- Molecular characterizations and customized biomarker assays
- Reference Lab service provision
- Contract Research Services
- Data management and reporting (using our validated LIMS system, SOPs, etc.)
- Regular reporting and progress meetings managed by dedicated project managers
- Rapid Start-up, Rapid Scale-up, Rapid Delivery
- CLIA-certified lab: committed to maintaining processes, standards, controls, and the quality of research and data
- Our team brings to the table hundreds of years of combined industry experience
Customized Services for Early-Stage Companies
At Gnome Sciences, we recognize the specific needs and challenges of startups. We offer competitive pricing to emerging life sciences and biotech/pharma enterprises without compromising our clinical-grade quality.
Common Studies for Startups Encompass:
Tailored Tissue Preparation
- Histopathology, including slide staining and imaging
- Biomarker characterization and cellular localization
- Pharmacogenomic Testing
- SNP analysis and gene expression analysis in biospecimens and cell lines
- Guidance for Clinical Laboratory Developed Test (LDT), such as COVID-19 PCR Testing
- Nucleic Acid Isolations and Sample/Library preparation for Whole Exome/Whole Genome Sequencing
- Support services for drug discovery and development: pharmacogenomics, mutational analysis in protein and pathway targets, impact of drugs on genome expression, etc.
Support for Virtual BioPharma Companies
We understand that early-stage life sciences companies are progressively adopting virtual models to enhance agility and minimize operational costs and investments. Nevertheless, these companies can’t afford to sacrifice the quality or speed of their R&D to reap these benefits. Gnome Sciences can undertake your lab work for individual steps/stages or collaborate with you throughout the entire product development process.
Grants & Publications
We’re more than willing to provide quotations for any of our studies or standard or bespoke laboratory services that you can incorporate into your grant applications (either as a supplier or as a research subcontractor). Our offering includes clinical-grade services to design, develop, and validate pathology methods, genomic assays, as well as a variety of molecular biology and advanced tissue biology services. We can assist you in obtaining the publication-quality data essential for that pivotal grant or manuscript you’re working on – the type of data that leaves no room for reviewer interpretation. We’re also ready to contract with you to deliver that compelling piece of preliminary data crucial to securing your grant.
